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Although the majority of chemicals in cosmetics pose limited or zero threat, several have been associated to serious health problems, including developmental delays and cancer. Chemicals in cosmetics invade the body through the skin, inhalation, ingestion and internal use, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in water, food, and a lot of other common products. Still, no area of consumer products is susceptible to less government inspection than cosmetics and other personal products, including Gel-n-Base in One Gel Polish - Spontaneous. Though many of the chemicals and contaminants in cosmetics and personal care products almost certainly present very little risk, exposure to a few is associated with serious health problems, including cancer.