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While the majority of chemicals in cosmetics pose little or absolutely no risk, dozens have been associated with substantial medical problems, such as neurological harm and cancer. Chemicals in cosmetics invade a person's body through the skin and inhalation, and pose the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in water, food, and several other everyday products. However, no classification of consumer products is accountable to less government oversight than cosmetics and other personal care products, including Gel-n-Base in One Gel Polish - Spontaneous. Although most of the chemicals and contaminants in cosmetics likely present very little risk, being exposed to a few has been linked to significant health problems, including cancer.