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While many chemicals in beauty products present hardly any or zero threat, dozens are linked with significant health problems, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals invade a person's body through the skin and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in water, food, and many other commonly used goods. Yet, no classification of consumer goods is accountable to less government direction than cosmetics and other personal care products, including Gel-n-Base in One Gel Polish - Avalanche. Though most of the contaminants and chemicals in cosmetics and personal care products in all likelihood pose minimal risk, exposure to some has been linked to significant health concerns, including cancer.