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Though many chemicals in cosmetics present limited or zero threat, some are linked to considerable medical conditions, including developmental delays and cancer. Cosmetic chemicals gain entry to a person's body through internal use, the skin, and inhalation, and pose similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and a lot of other ordinary goods. But, no area of consumer goods is accountable to less government direction than cosmetics and other personal products, including Gel-n-Base in One Gel Polish - Innocence. While many of the contaminants and chemicals in cosmetics and personal care products almost certainly present very little risk, exposure to a few has been associated with significant health disorders, including cancer.