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Although the majority of chemicals in cosmetics present slight or zero threat, dozens are associated to severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals enter a person's body through the skin, inhalation, ingestion and internal use, and pose similar problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food and lots of other common products. But, no area of consumer products is susceptible to less government oversight than cosmetics, including Bullish on OPI. Although many of the chemicals and contaminants in cosmetics and personal care products in all likelihood pose minimal risk, being exposed to a few is associated with worrying health disorders, such as cancer.