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While most chemicals in cosmetics present little or no threat, several dozen are linked with significant medical conditions, such as cancer, and neurological harm. Cosmetic chemicals enter the body through inhalation, ingestion, and the skin, and lead to similar dangers as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and several other commonly used items. Yet, no kind of consumer items is susceptible to less government inspection than cosmetics, including Maniac. Though many of the contaminants and chemicals in cosmetics most likely present little risk, exposure to some has been associated with substantial health problems, such as cancer.