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While many chemicals in cosmetics present limited or no risk, several dozen are associated with serious medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics invade a person's body through internal use, the skin, and inhalation, and pose the same dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and various other commonly used items. Still, no classification of consumer items is susceptible to less government management than cosmetics, including Sally Hansen Satin Glam. While many of the chemicals in cosmetics very likely pose little risk, exposure to a few has been associated with critical health disorders, such as cancer.