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While many chemicals in cosmetic products present little or zero threat, several dozen have been linked with substantial medical problems, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter the body through the skin, inhalation, ingestion and internal use, and cause the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food, water, and various other ordinary products. Still, no classification of consumer products is subject to less government management than cosmetics, including Calendar Girl. Although most of the contaminants and chemicals in cosmetics and personal care products most likely present very little risk, subjection to a few has been associated with significant health concerns, such as cancer.