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Though the majority of chemicals in cosmetic products pose slight or no danger, some have been associated to considerable medical problems, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through inhalation, ingestion, and the skin, and lead to the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and lots of other commonly used goods. But, no classification of consumer goods is accountable to less government management than cosmetics and other personal care products, including Calendar Girl. Although most of the chemicals and contaminants in cosmetics likely present little risk, exposure to a few is associated with significant health issues, such as cancer.