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While most chemicals in cosmetics pose slight or zero risk, some are associated to serious medical issues, such as cancer, and neurological harm. Chemicals in cosmetics can enter a person's body through ingestion, inhalation, and internal use, and cause similar dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food and many other commonly used items. Still, no type of consumer items is subject to less government inspection than cosmetics and other personal care products, including SkinPerfect Primer SPF30. While many of the contaminants and chemicals in cosmetics almost certainly pose minimal risk, subjection to some is associated with substantial health concerns, including cancer.