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Though many chemicals in cosmetics pose very little or no risk, dozens have been associated to significant health issues, including cancer, and neurological harm. Chemicals in cosmetics gain entry to the body through ingestion, inhalation, and internal use, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food, water, and several other everyday items. Still, no group of consumer items is subject to less government direction than cosmetics and other personal products, including Trugel Lookin' Good. While most of the contaminants and chemicals in cosmetics and personal care products likely present very little risk, subjection to some has been associated with worrying health concerns, including cancer.