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Although many chemicals in cosmetics pose hardly any or zero risk, several have been linked to significant health conditions, including neurological harm and cancer. Cosmetic chemicals invade a person's body through inhalation, ingestion, and the skin, and pose similar problems as food chemicals, per this site.

Chemicals linked to cancer can be found in food, water, and various other commonly used products. Yet, no sector of consumer products is accountable to less government direction than cosmetics, including Tickled Nail Lacquer. Although many of the chemicals in cosmetics and personal care products likely present little risk, exposure to some is linked to major health issues, such as cancer.