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While most chemicals in beauty products and cosmetics present minimal or no threat, several dozen are associated to serious health problems, such as developmental delays and cancer. Cosmetic chemicals gain entry to a person's body through the skin, inhalation, ingestion and internal use, and cause similar dangers as food chemicals, per this site.

Chemicals associated with cancer are found in food and various other ordinary goods. Still, no area of consumer goods is susceptible to less government inspection than cosmetics, including Toe-Tally Textured Lacquer. Although most of the chemicals in cosmetics and personal care products almost certainly present minimal risk, subjection to some has been associated with critical health problems, including cancer.