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Although the majority of chemicals in cosmetic products present very little or absolutely no risk, dozens have been associated with substantial medical conditions, including neurological harm and cancer. Cosmetic chemicals get into a person's body through inhalation, the skin, and ingestion, and pose similar problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food, water, and several other commonly used products. However, no sector of consumer products is subject to less government direction than cosmetics, including Orange A-Peel Lacquer. Although most of the contaminants and chemicals in cosmetics and personal care products most likely present minimal risk, exposure to a few has been linked to worrying health conditions, including cancer.