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Though most chemicals in cosmetics present limited or absolutely no risk, dozens are associated to serious health problems, such as neurological harm and cancer. Cosmetic chemicals invade a person's body through inhalation, the skin, and ingestion, and pose similar risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food and a lot of other ordinary products. However, no sector of consumer products is subject to less government inspection than cosmetics and other personal care products, including Tangerine Twist Lacquer. Though many of the chemicals and contaminants in cosmetics probably present minimal risk, exposure to a few has been associated with major health issues, such as cancer.