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Though the majority of chemicals in cosmetics pose hardly any or absolutely no threat, dozens have been associated with severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter the body through inhalation, ingestion, and the skin, and pose similar risks as food chemicals, per this site.

Chemicals linked to cancer can be found in food and many other common products. However, no group of consumer products is susceptible to less government oversight than cosmetics, including High Five Lacquer. While many of the chemicals and contaminants in cosmetics in all likelihood present little risk, being exposed to a few is linked to serious health conditions, including cancer.