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Although the majority of chemicals in beauty products present slight or no threat, dozens have been linked with significant health problems, including cancer, and neurological harm. Chemicals in cosmetics enter a person's body through inhalation, ingestion, and the skin, and cause similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and various other commonly used goods. However, no category of consumer goods is susceptible to less government inspection than cosmetics, including Pearlie Pink Lacquer. Though most of the chemicals in cosmetics and personal care products almost certainly pose minimal risk, exposure to a few has been associated with significant health problems, including cancer.