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While most chemicals in beauty products present little or zero threat, several dozen are associated to serious health problems, including developmental delays and cancer. Chemicals in cosmetics gain entry to the body through inhalation, ingestion, and the skin, and pose similar problems as food chemicals, per this site.

Chemicals linked to cancer can be found in water, food, and many other common items. However, no group of consumer items is subject to less government oversight than cosmetics and other personal products, including Signature. Though many of the chemicals and contaminants in cosmetics very likely present little risk, exposure to a few has been linked to substantial health problems, such as cancer.