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Although many chemicals in beauty products and cosmetics present little or zero danger, several have been associated with considerable medical problems, including developmental delays and cancer. Cosmetic chemicals gain entry to a person's body through ingestion, inhalation, and internal use, and lead to similar dangers as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and various other ordinary goods. However, no area of consumer goods is susceptible to less government oversight than cosmetics, including Trugel Blue Topaz. Though most of the contaminants and chemicals in cosmetics almost certainly pose very little risk, exposure to a few is associated with critical health problems, such as cancer.