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While the majority of chemicals in beauty products present hardly any or zero danger, some have been associated to substantial medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter the body through internal use, the skin, and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals associated with cancer are found in food, water, and several other commonly used goods. However, no category of consumer goods is susceptible to less government management than cosmetics and other personal products, including Trugel Patina. While most of the chemicals and contaminants in cosmetics and personal care products almost certainly pose minimal risk, exposure to a few is associated with serious health issues, such as cancer.