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Although most chemicals in cosmetics present minimal or no risk, several dozen are associated to serious health conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through ingestion, inhalation, and internal use, and pose similar problems as food chemicals, per this site.

Chemicals associated with cancer can be found in water, food, and a lot of other ordinary products. However, no area of consumer products is subject to less government management than cosmetics, including Trugel Baby Doll. Though most of the contaminants and chemicals in cosmetics likely pose little risk, exposure to some has been associated with substantial health issues, including cancer.