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Though many chemicals in beauty products pose hardly any or no threat, several dozen have been associated to severe medical issues, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics invade a person's body through inhalation, ingestion, and the skin, and lead to similar problems as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and a lot of other commonly used items. However, no classification of consumer items is susceptible to less government oversight than cosmetics and other personal products, including Trugel Matador. While most of the chemicals in cosmetics and personal care products likely pose little risk, exposure to some has been associated with serious health issues, including cancer.