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Although the majority of chemicals in cosmetics present hardly any or zero threat, dozens are associated with severe health problems, such as developmental delays and cancer. Chemicals in cosmetics enter a person's body through internal use, the skin, and inhalation, and lead to the same problems as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and many other commonly used items. However, no sector of consumer items is accountable to less government management than cosmetics and other personal products, including Trugel Burnt Sienna. Though many of the contaminants and chemicals in cosmetics very likely pose very little risk, subjection to a few is associated with serious health conditions, such as cancer.