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While many chemicals in beauty products and cosmetics present minimal or absolutely no danger, several dozen have been associated to serious health conditions, such as cancer, and neurological harm. Chemicals in cosmetics can enter the body through inhalation, the skin, and ingestion, and cause the same risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food and many other everyday items. Still, no group of consumer items is subject to less government management than cosmetics, including Nail Lacquer Notorious. While most of the chemicals in cosmetics probably pose little risk, being exposed to some is linked to serious health issues, such as cancer.