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Though many chemicals in cosmetics present limited or zero threat, dozens are associated to severe health conditions, including developmental delays and cancer. Chemicals in cosmetics enter a person's body through internal use, the skin, and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals associated with cancer are found in food and a lot of other everyday products. However, no area of consumer products is accountable to less government direction than cosmetics, including That's All Bright with Me. Although most of the contaminants and chemicals in cosmetics and personal care products almost certainly pose minimal risk, being exposed to a few has been associated with substantial health disorders, such as cancer.