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While the majority of chemicals in beauty products and cosmetics pose minimal or zero risk, several have been associated with substantial medical problems, including developmental delays and cancer. Cosmetic chemicals can enter a person's body through ingestion, inhalation, and internal use, and cause similar problems as food chemicals, per this site.

Chemicals linked to cancer can be found in food and many other ordinary goods. However, no type of consumer goods is accountable to less government direction than cosmetics, including Don't Melbourne the Toast. While many of the chemicals in cosmetics likely present very little risk, exposure to a few is linked to serious health problems, including cancer.