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Although most chemicals in cosmetics present very little or no risk, some are associated to significant medical problems, including neurological harm and cancer. Chemicals in cosmetics invade a person's body through internal use, the skin, and inhalation, and lead to similar dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and many other common items. Still, no sector of consumer items is subject to less government inspection than cosmetics and other personal care products, including Decades of Shades. While most of the chemicals and contaminants in cosmetics in all likelihood pose minimal risk, being exposed to some is associated with critical health disorders, including cancer.