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While the majority of chemicals in cosmetics pose little or no threat, several dozen have been associated to significant health conditions, such as cancer, and neurological harm. Cosmetic chemicals enter a person's body through ingestion, inhalation, and internal use, and pose similar problems as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and various other common goods. However, no classification of consumer goods is susceptible to less government inspection than cosmetics, including PASTELf. Though many of the contaminants and chemicals in cosmetics and personal care products probably present very little risk, subjection to a few has been associated with worrying health issues, such as cancer.