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Though most chemicals in cosmetics pose slight or absolutely no risk, several have been associated to substantial medical issues, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals invade the body through the skin and inhalation, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in food, water, and a lot of other common items. However, no sector of consumer items is accountable to less government direction than cosmetics and other personal care products, including Big Calm Jelly. While many of the chemicals and contaminants in cosmetics almost certainly pose minimal risk, exposure to some has been linked to critical health conditions, such as cancer.