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While most chemicals in beauty products present slight or no risk, several dozen have been linked to substantial medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through inhalation, the skin, and ingestion, and lead to similar dangers as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and several other commonly used products. However, no sector of consumer products is subject to less government oversight than cosmetics, including Skylight. While many of the chemicals in cosmetics most likely present little risk, being exposed to some has been associated with worrying health issues, including cancer.