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Although most chemicals in cosmetics pose hardly any or zero threat, several have been associated to serious health problems, including developmental delays and cancer. Chemicals in cosmetics enter the body through ingestion, inhalation, and internal use, and cause similar risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food, water, and various other everyday items. Still, no classification of consumer items is susceptible to less government management than cosmetics and other personal care products, including Plum Crazy. While most of the chemicals and contaminants in cosmetics and personal care products most likely present little risk, exposure to some has been linked to major health issues, such as cancer.