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While many chemicals in cosmetics present hardly any or no risk, several dozen are linked with severe health problems, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through inhalation, ingestion, and the skin, and cause the same problems as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and various other common goods. Yet, no kind of consumer goods is subject to less government inspection than cosmetics, including Fifth Avenue. While many of the chemicals in cosmetics very likely pose little risk, being exposed to some has been linked to significant health disorders, including cancer.