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Although most chemicals in cosmetic products present slight or zero threat, several are linked with serious medical conditions, such as developmental delays and cancer. Chemicals in cosmetics invade a person's body through inhalation, the skin, and ingestion, and lead to the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food, water, and a lot of other common items. Yet, no category of consumer items is accountable to less government inspection than cosmetics, including Base Coat. Though many of the chemicals in cosmetics and personal care products in all likelihood pose very little risk, being exposed to a few has been associated with significant health disorders, such as cancer.