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Though many chemicals in cosmetics present minimal or absolutely no danger, dozens have been associated to severe health issues, including developmental delays and cancer. Chemicals in cosmetics gain entry to the body through the skin, inhalation, ingestion and internal use, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in water, food, and several other common products. Still, no group of consumer products is subject to less government oversight than cosmetics and other personal products, including 45 Second Top Coat. Although most of the chemicals in cosmetics in all likelihood pose minimal risk, being exposed to some is linked to significant health conditions, including cancer.