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While most chemicals in cosmetics pose little or no threat, dozens are linked to severe health problems, such as neurological harm and cancer. Cosmetic chemicals gain entry to the body through internal use, the skin, and inhalation, and cause the same problems as food chemicals, per this site.

Chemicals associated with cancer can be found in food and lots of other commonly used goods. But, no area of consumer goods is subject to less government oversight than cosmetics, including 45 Second Top Coat. Although most of the contaminants and chemicals in cosmetics and personal care products almost certainly present minimal risk, being exposed to some is associated with critical health disorders, including cancer.