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Although many chemicals in cosmetics present minimal or zero risk, several dozen have been associated with severe health conditions, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through inhalation, ingestion, and the skin, and cause similar problems as food chemicals, per this site.

Chemicals associated with cancer can be found in water, food, and many other everyday items. Still, no group of consumer items is susceptible to less government inspection than cosmetics and other personal products, including Sunscreen Top Coat. While most of the contaminants and chemicals in cosmetics probably present little risk, being exposed to some is associated with significant health concerns, including cancer.