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While the majority of chemicals in cosmetic products present minimal or zero threat, several dozen are linked to serious health issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics get into a person's body through inhalation, ingestion, and the skin, and cause the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in food and lots of other common items. Still, no area of consumer items is accountable to less government inspection than cosmetics, including Base Coat. Although most of the chemicals in cosmetics almost certainly pose little risk, your exposure to a few has been associated with significant health concerns, including cancer.