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While the majority of chemicals in cosmetics present slight or no risk, dozens have been associated to substantial health conditions, including cancer, and neurological harm. Cosmetic chemicals gain entry to a person's body through the skin and inhalation, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in water, food, and a lot of other commonly used goods. However, no area of consumer goods is susceptible to less government direction than cosmetics, including Base Coat. Though many of the chemicals in cosmetics and personal care products almost certainly present very little risk, being exposed to some has been linked to serious health conditions, such as cancer.