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Although the majority of chemicals in cosmetic products present little or zero danger, several have been associated to substantial health conditions, including developmental delays and cancer. Cosmetic chemicals enter a person's body through the skin and inhalation, and lead to the same dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food and several other commonly used goods. However, no type of consumer goods is susceptible to less government management than cosmetics and other personal care products, including Knotty Laquer. While most of the chemicals in cosmetics and personal care products very likely pose very little risk, being exposed to a few has been associated with worrying health concerns, such as cancer.