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While many chemicals in beauty products present limited or zero risk, several are associated to considerable medical issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter a person's body through the skin, inhalation, ingestion and internal use, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in water, food, and various other common products. However, no group of consumer products is susceptible to less government oversight than cosmetics and other personal care products, including Manicure in a Bottle. While many of the chemicals in cosmetics and personal care products in all likelihood present little risk, subjection to some has been associated with critical health disorders, including cancer.