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Though the majority of chemicals in beauty products present minimal or no risk, several are linked with serious health issues, such as neurological harm and cancer. Cosmetic chemicals can enter a person's body through ingestion, inhalation, and internal use, and lead to similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and several other everyday items. Still, no category of consumer items is subject to less government inspection than cosmetics, including Mainstream Soak Off Gel Polish. Though many of the contaminants and chemicals in cosmetics and personal care products probably pose little risk, exposure to a few is associated with serious health issues, such as cancer.