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While most chemicals in cosmetics pose minimal or zero threat, several dozen have been associated to severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through ingestion, inhalation, and internal use, and pose the same dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food and lots of other everyday items. But, no classification of consumer items is accountable to less government direction than cosmetics, including Midnight Spree Soak Off Gel Polish. Though most of the chemicals and contaminants in cosmetics and personal care products in all likelihood present little risk, being exposed to a few is associated with major health conditions, such as cancer.