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Although many chemicals in cosmetics present slight or zero danger, some are associated to substantial health issues, including cancer, and neurological harm. Cosmetic chemicals enter a person's body through internal use, the skin, and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals linked to cancer are found in food and various other common products. Yet, no area of consumer products is susceptible to less government direction than cosmetics, including Rouge Soak Off Gel Polish. While most of the contaminants and chemicals in cosmetics and personal care products in all likelihood pose very little risk, subjection to a few has been linked to substantial health concerns, such as cancer.