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While many chemicals in beauty products present little or absolutely no threat, several dozen have been associated to considerable health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals invade the body through inhalation, ingestion, and the skin, and lead to similar problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food and several other common items. Still, no classification of consumer items is susceptible to less government oversight than cosmetics, including English Saddle Brown Gel Polish. Though most of the contaminants and chemicals in cosmetics and personal care products very likely present very little risk, being exposed to a few has been associated with critical health disorders, including cancer.