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Although the majority of chemicals in cosmetic products present little or zero threat, several dozen are associated to considerable medical problems, including cancer, and neurological harm. Chemicals in cosmetics invade a person's body through inhalation, ingestion, and the skin, and cause similar dangers as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and lots of other common items. Still, no group of consumer items is accountable to less government direction than cosmetics and other personal care products, including Pearl Shimmer Gel Polish. Though many of the contaminants and chemicals in cosmetics and personal care products most likely present minimal risk, subjection to a few has been associated with serious health concerns, such as cancer.