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Although most chemicals in cosmetics present minimal or zero threat, some are associated to severe medical conditions, such as neurological harm and cancer. Cosmetic chemicals get into the body through ingestion, inhalation, and internal use, and cause the same risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in water, food, and various other commonly used goods. Yet, no area of consumer goods is susceptible to less government oversight than cosmetics, including Twinkling Periwinkle. Although most of the contaminants and chemicals in cosmetics and personal care products likely pose very little risk, exposure to some is linked to critical health issues, including cancer.