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Although the majority of chemicals in cosmetic products present minimal or zero threat, several are associated with substantial medical problems, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through the skin and inhalation, and lead to similar problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food, water, and various other ordinary products. However, no sector of consumer products is subject to less government oversight than cosmetics and other personal products, including On Screen Kiss Color Gel. Though most of the chemicals and contaminants in cosmetics in all likelihood pose minimal risk, exposure to some is linked to critical health problems, such as cancer.