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While the majority of chemicals in cosmetics pose slight or absolutely no threat, several have been linked with severe medical problems, including developmental delays and cancer. Chemicals in cosmetics get into a person's body through inhalation, ingestion, and the skin, and pose the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food, water, and many other commonly used items. Still, no kind of consumer items is accountable to less government direction than cosmetics, including Gel Polish Rhubarb. Though many of the chemicals and contaminants in cosmetics and personal care products almost certainly present very little risk, subjection to a few has been associated with worrying health concerns, such as cancer.