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Although the majority of chemicals in cosmetics pose very little or zero danger, dozens are associated with substantial health problems, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through the skin and inhalation, and lead to the same risks as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and various other commonly used goods. Yet, no classification of consumer goods is subject to less government management than cosmetics, including Gel Polish Rhubarb. Though most of the contaminants and chemicals in cosmetics likely present little risk, exposure to a few is associated with substantial health concerns, such as cancer.