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Although the majority of chemicals in cosmetics present limited or no threat, dozens are associated with severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through inhalation, the skin, and ingestion, and cause similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food, water, and several other common items. However, no kind of consumer items is subject to less government inspection than cosmetics, including Little Drummer Boy. Although most of the chemicals in cosmetics likely pose very little risk, subjection to some is associated with major health problems, including cancer.