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While the majority of chemicals in cosmetic products present limited or zero danger, dozens are linked with severe medical problems, including neurological harm and cancer. Cosmetic chemicals invade the body through internal use, the skin, and inhalation, and pose the same problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food, water, and several other everyday goods. Still, no group of consumer goods is subject to less government oversight than cosmetics and other personal care products, including It's Up To Blue. Though most of the contaminants and chemicals in cosmetics likely pose very little risk, subjection to some has been linked to substantial health issues, including cancer.