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Though the majority of chemicals in beauty products pose limited or absolutely no threat, several have been linked to serious health conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals enter a person's body through ingestion, inhalation, and internal use, and lead to the same problems as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and several other common items. Yet, no area of consumer items is accountable to less government inspection than cosmetics, including One Night Stand. While most of the chemicals and contaminants in cosmetics and personal care products very likely pose minimal risk, subjection to some is linked to substantial health issues, including cancer.