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Though the majority of chemicals in cosmetics pose minimal or zero risk, dozens are associated with substantial medical issues, including neurological harm and cancer. Cosmetic chemicals can enter a person's body through inhalation, ingestion, and the skin, and pose the same risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and many other commonly used products. Yet, no sector of consumer products is accountable to less government inspection than cosmetics, including Autograph Gel Polish. Although many of the chemicals and contaminants in cosmetics and personal care products in all likelihood present little risk, subjection to a few has been associated with critical health problems, including cancer.