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While many chemicals in beauty products present slight or absolutely no risk, several have been associated to significant medical problems, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics invade a person's body through the skin, inhalation, ingestion and internal use, and pose similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and many other commonly used items. But, no group of consumer items is accountable to less government oversight than cosmetics, including Pistachio Gel Polish. Although most of the contaminants and chemicals in cosmetics probably present minimal risk, being exposed to a few has been associated with critical health issues, including cancer.