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Although many chemicals in cosmetic products present limited or zero risk, dozens have been associated with substantial health conditions, including cancer, and neurological harm. Cosmetic chemicals gain entry to a person's body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food, water, and several other common items. However, no sector of consumer items is susceptible to less government management than cosmetics and other personal products, including Pistachio Gel Polish. Though most of the contaminants and chemicals in cosmetics and personal care products likely present little risk, exposure to a few has been associated with major health problems, such as cancer.